Dry Eye Homepage

1. The definition and classification of dry eye disease: report of the definition and classification subcommittee of the International Dry Eye Workshop (2007). Ocul Surf. 2007;5(2):75-92.
2. Chang AY, Purt B. Biochemistry, tear film. In: StatPearls. StatPearls Publishing; 2023.
3. Tears chemistry stock vector (Royalty free) 128669366. Shutterstock.
4. Rouen PA, White ML. Dry eye disease: prevalence, assessment, and management. Home Healthc Now. 2018;36(2):74-83.
5. Matossian C, McDonald M, Donaldson KE, et al. Dry eye disease: consideration for women’s health. J Womens Health (Larchmt). 2019;28(4):502-514.
6. Barabino S. Is dry eye disease the same in young and old patients? A narrative review of the literature. BMC Ophthalmology. 2022;22(1):85.

Do I Have Dry Eye Disease?

1. Marshall LL, Roach JM. Treatment of dry eye disease. Consult Pharm. 2016;31(2):96-106.
2. All Wales Therapeutics and Toxicology Centre. Dry eye syndrome guidance (2016). Pages 1-11.
3. Ethis Communications, Inc. The definition and classification of dry eye disease: report of the definition and classification subcommittee of the international Dry Eye Workshop (2007). Ocul Surf. 2007;5(2):75-92.
4. National Eye Institute. Testing for dry eye (2021). Accessed July 25, 2023. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/dry-eye/testing-dry-eye.
5. Matossian C, McDonald M, Donaldson KE, et al. Dry eye disease: consideration for women’s health. J Womens Health (Larchmt). 2019;28(4):502-514.

Types of Dry Eye Disease

1. The definition and classification of dry eye disease: report of the definition and classification subcommittee of the international Dry Eye Workshop (2007). Ocul Surf. 2007;5(2):75-92.
2. Marshall LL, Roach JM. Treatment of dry eye disease. Consult Pharm. 2016;31(2):96-106.
3. All Wales Therapeutics and Toxicology Centre. Dry eye syndrome guidance (2016). Pages 1-11.
4. Rouen PA, White ML. Dry eye disease: prevalence, assessment, and management. Home Healthc Now. 2018;36(2):74-83.
5. Chang AY, Purt B. Biochemistry, tear film. In: StatPearls. StatPearls Publishing; 2023.
6. Matossian C, McDonald M, Donaldson KE, et al. Dry eye disease: consideration for women’s health. J Womens Health (Larchmt). 2019;28(4):502-514.
7. Tear film formation stock illustration 128156006. Shutterstock.
8. TheFreeDictionary.com. Lens aperture. Accessed July 28, 2023. https://medical-dictionary.thefreedictionary.com/Lens+aperture.
9. The Free Dictionary. Topical. Accessed July 28, 2023. https://medical-dictionary.thefreedictionary.com/topical.
10. Wills Eye Hospital. Ocular surface disease. Accessed July 28, 2023. https://www.willseye.org/ocular-surface-disease/.
11. Medlineplus Medical Encyclopedia. Allergic conjunctivitis. Accessed July 28, 2023. https://medlineplus.gov/ency/article/001031.htm.
12. RxList. Medical definition of lacrimal gland.  Accessed July 28, 2023. https://www.rxlist.com/lacrimal_gland/definition.htm.

Treating and Managing Dry Eye Disease

1. Rouen PA, White ML. Dry eye disease: prevalence, assessment, and management. Home Healthc Now. 2018;36(2):74-83.
2. Marshall LL, Roach JM. Treatment of dry eye disease. Consult Pharm. 2016;31(2):96-106.
3. All Wales Therapeutics and Toxicology Centre. Dry eye syndrome guidance (2016). Pages 1-11.
4. Kangari H, Eftekhari MH, Sardari S, et al. Short-term consumption of oral omega-3 and dry eye syndrome. Ophthalmology. 2013;120(11):2191-2196.
5. Bae SH, Shin YJ, Kim HK, et al. Vitamin D supplementation for patients with dry eye syndrome refractory to conventional treatment. Sci Rep. 2016;6:33083.
6. Alanazi SA, El-Hiti GA, Al-Baloud AA, et al. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Clin Ophthalmol. 2019;13:599-604.
7. The definition and classification of dry eye disease: report of the definition and classification subcommittee of the international Dry Eye Workshop (2007). Ocul Surf. 2007;5(2):75-92.
8. RxList. Medical definition of meibomian gland. Accessed July 28, 2023. https://www.rxlist.com/meibomian_gland/definition.htm.

Tips and Resources for Dry Eye Disease

1. All Wales Therapeutics and Toxicology Centre. Dry eye syndrome guidance (2016). Pages 1-11.
2. Rouen PA, White ML. Dry eye disease: prevalence, assessment, and management. Home Healthcare Now. 2018;36(2):74-83.
3. Tandon R, Vashist P, Gupta N, et al. Association of dry eye disease and sun exposure in geographically diverse adult (≥40 years) populations of India: the SEED (Sun exposure, environment and dry eye disease) study – second report of the ICMR-EYE SEE study group. The Ocular Surface. 2020;18(4):718-730.
4. Marshall LL, Roach JM. Treatment of dry eye disease. Consult Pharm. 2016;31(2):96-106.
5. Kangari H, Eftekhari MH, Sardari S, et al. Short-term consumption of oral omega-3 and dry eye syndrome. Ophthalmology. 2013;120(11):2191-2196.
6. Omega-3 fatty acids. NIH Office of Dietary Supplements. Accessed July 27, 2023. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/.
7. Bae SH, Shin YJ, Kim HK, et al. Vitamin D supplementation for patients with dry eye syndrome refractory to conventional treatment. Sci Rep. 2016;6:33083.
8. NIH Office of Dietary Supplements. Vitamin D. Accessed July 27, 2023. https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/.
9. Alanazi SA, El-Hiti GA, Al-Baloud AA, et al. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Clin Ophthalmol. 2019;13:599-604.
10. NIH Office of Dietary Supplements. Vitamin A and carotenoids. Accessed July 27, 2023. https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/.
11. American Optometric Association. Computer vision syndrome (digital eye strain). Accessed July 27, 2023. https://www.aoa.org/healthy-eyes/eye-and-vision-conditions/computer-vision-syndrome.

Visu Products for Dry Eye Disease

1. VISUXL^®. Approved Package Leaflet. September 2017.
2. VisuXL^® Gel Approved Package Leaflet. Instructions for use.
3. VisuEVO^® Approved Package Leaflet. Information for the user.
4. VISUXL^® Instructions for use. Data on file. – copy & ref from supplied element (provided in ref pack)
5. VisuXL^® Gel Approved Package Leaflet. Instructions for use.– copy & ref from supplied element (provided in ref pack)

Product legals

VisuXL^® 10 ml bottle. Composition: 100 ml of VisuXL^® contains: 100 mg of cross-linked hyaluronic acid sodium salt; 100 mg of Coenzyme Q10; 500 mg of Vitamin E TPGS (D-a-tocopheryl-polyethylene glycol 1000 succinate); buffered isotonic solution up to 100 ml.

VisuXL^® Gel. Composition: Each 100 ml of VisuXL^® Gel contains: Coenzyme Q10 100 mg, Vitamin E TPGS (D-a-tocopheryl-polyethylene glycol 1000 succinate) 500 mg cross-linked sodium Carboxymethylcellulose 400 mg, Poloxamer 407 9000 mg, Disodium EDTA 100 mg, buffered isotonic solution q.s. to 100 ml.

VisuEVO^® Opthalmic Solution. Composition: Liposomes from soya phospholipids, algae oil (DHA+EPA), Vitamin A palmitate, Vitamin D, disodium EDTA, PEG 400, Boric acid, Sodium tetraborate; buffered isotonic buffered with pH 7.20.

For full prescribing information refer to the approved package inserts.

Applicant: Genop Healthcare (Pty) Ltd. PO BOX 3911, Halfway House, 1685, South Africa. Tel: 0861 436 674. Co. Reg. No. 1984/011575/07. www.genop.co.za

Marketed by: Adcock Ingram Limited. Reg. No. 1949/034385/06. Private Bag X69, Bryanston, 2021, South Africa. Customer Care: 0860 ADCOCK / 232625. www.adcock.com

Xailin Products for Dry Eye Disease

1. Xailin^® Plus Package Insert, VisuFarma November 2021.
2. Xailin^® Gel Package Insert, VisuFarma November 2016.
3. Xailin^® Night Package Insert, VisuFarma December 2016.
4. Xailin^® Fresh Package Insert, VisuFarma February 2017.
5. Xailin^® Hydrate Package Insert, VisuFarma November 2016.

Applicant: Genop Healthcare (Pty) Ltd. PO BOX 3911, Halfway House, 1685, South Africa. Tel: 0861 436 674. Co. Reg. No. 1984/011575/07. www.genop.co.za

Marketed by: Adcock Ingram Limited. Reg. No. 1949/034385/06. Private Bag X69, Bryanston, 2021, South Africa. Customer Care: 0860 ADCOCK / 232625. www.adcock.com